Risperidone can weaken how well levodopa works. Levodopa is used to treat Parkinson's disease, so if the two are taken together, Parkinson's symptoms such as stiffness, tremor and slow movement may get worse. Ask your doctor before combining them.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor before taking them together. Watch for worse stiffness, tremor or slow movement, and tell your doctor if it happens.