Drospi Drospirenone Rifampicin
ModerateSome medicines and herbal products can make hormonal contraceptives (HCs), like Drospirenone, work less well. These include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, rifabutin, rufinamide, aprepitant, and products containing St. Rifampicin is on this list, so taking it together with Drospirenone may lower the effectiveness of the HC.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.