Lopenta 100 Tapentadol Clobazam
MajorOpioid plus benzodiazepine causes profound sedation, respiratory depression, coma and death.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid if possible. Otherwise use the lowest doses for the shortest time and monitor breathing.