Rizonib Crizotinib Phenobarbital
MajorPhenobarbital speeds up the liver enzyme that breaks down many medicines, so the body clears crizotinib faster. The leaflet says to avoid taking crizotinib with medicines like phenobarbital.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Do not take these together unless your doctor has said so. Tell your doctor before starting crizotinib if you take phenobarbital.