Dezco Deflazacort Itraconazole
MajorStrong CYP3A4 inhibition markedly raises active deflazacort metabolite, increasing corticosteroid adverse effects.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Reduce deflazacort dose to one-third, or avoid. Monitor for steroid toxicity.