Pulmosis Pirfenidone Ciprofloxacin
ModeratePirfenidone and ciprofloxacin taken together can raise the amount of pirfenidone in the body. Ciprofloxacin slows down the enzyme CYP1A2, which breaks pirfenidone down, so the drug stays in the blood for longer. This can also change which side effects you are likely to get from pirfenidone.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.