Emestop 125 Aprepitant Rifampicin
ModerateBe careful when taking Aprepitant (sold as Vomend) with other medicines that are broken down by the CYP3A4 or CYP2C9 enzymes. Rifampin is one of them. Others on the same list include warfarin, tolbutamide, phenytoin, ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, nelfinavir, diltiazem and carbamazepine.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.