Lino-M 850 Linagliptin + Metformin Hydrochloride Ranitidine
ModerateRanitidine is a cationic drug that the kidneys clear through tubular secretion. Metformin in Linagliptin + Metformin uses the same transport system in the kidney tubules, so in theory the two could compete with each other and interact.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.