Linatab M 2.5/1000 Linagliptin + Metformin Hydrochloride Metformin
ModerateMedicines like amiloride, digoxin, morphine, quinidine, ranitidine, trimethoprim and vancomycin are cleared by the kidneys through the same tubule transport system that metformin uses. In theory, they can compete with metformin for that system, so the combination could interact. This is a theoretical risk the leaflet describes, not a proven effect.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.