Phenadryl-10 Vet Diphenhydramine Hydrochloride Rivastigmine Tartrate
ModerateThe anticholinergic effect of diphenhydramine opposes the cholinesterase inhibitor and reduces efficacy.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
Clinical management: Avoid combination. Use a non-sedating antihistamine.