Rocular Brimonidine Tartrate Clonidine Hydrochloride
ModerateThe leaflet text for brimonidine does not say anything about how brimonidine and clonidine act when taken together. It only mentions tricyclic antidepressants, which are a different group of medicines, so there is no brimonidine and clonidine interaction to report from this text.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.