Erlonix Erlotinib Ciprofloxacin
ModerateWhen Erlotinib is taken with Ciprofloxacin, the level of Erlotinib in the blood goes up. The total exposure [AUC] rose by 39%, and the highest concentration [Cmax] rose by 17%. Ciprofloxacin slows down two liver enzymes, CYP3A4 and CYP1A2, which are the ones that normally break Erlotinib down, so more of it stays in the body.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.