Sertal-25 Sertraline Amitriptyline Hydrochloride
MajorSertraline may raise tricyclic levels; additive serotonergic and QT effects.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Monitor for toxicity and ECG; reduce amitriptyline dose if needed.