Dual renin-angiotensin blockade increases hyperkalaemia, hypotension and acute kidney injury risk.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid routine combination; if used, monitor potassium and renal function closely.