Rimpacin Rifampicin Ledipasvir + Sofosbuvir
MajorThe leaflet text on this pair is cut off, so it doesn't say what happens when ledipasvir and sofosbuvir are taken with rifampicin. All it shows is that rifampicin (listed as rifampin) is named among the P-gp inducers in the interaction warning for this medicine. The effect and any advice are not stated.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.