Cipromet Ciprofloxacin Venetoclax
MajorVenetoclax should not be taken together with strong CYP3A inhibitors such as itraconazole, ketoconazole, posaconazole, voriconazole, clarithromycin or ritonavir, either when treatment starts or while the dose is being built up, because this raises the risk of TLS (tumour lysis syndrome). Ciprofloxacin is a moderate CYP3A inhibitor, so during the start of treatment and the dose-building phase, taking it with venetoclax should be avoided.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.