Citapram Citalopram Hydrobromide Phenytoin Sodium
ModeratePhenytoin can lower the level and the effect of citalopram. It does this because citalopram is a CYP2C19 substrate, meaning it is broken down by the CYP2C19 enzyme, which phenytoin affects.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.