D Aspirin Aspirin Ketoprofen
MajorIncreased GI bleeding risk; ketoprofen may interfere with aspirin's antiplatelet effect.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid combination where possible; use gastroprotection.