Repaglid Repaglinide Phenobarbital
ModeratePhenobarbital belongs to a group of medicines called enzyme inducers, which speed up the cytochrome P450 enzyme system (P450). When it is taken with repaglinide, the body may break repaglinide down faster, so its effect can wear off sooner than expected.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.