Lopesim Loperamide + Simethicone Ritonavir
ModerateRitonavir can raise loperamide levels in your blood by 2 to 3 times. In a study, a 16 mg dose of loperamide was given with ritonavir, and quinidine had the same effect. Both of these medicines block P-glycoprotein.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.