Giane Cyproterone Acetate + Ethinyl Estradiol Phenylbutazone
ModeratePhenylbutazone may make Cyproterone Acetate + Ethinyl Estradiol less effective. If you take the two together, you may also have more breakthrough bleeding, meaning bleeding or spotting between your periods.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.