Pelex Ponatinib Hydrochloride Carbamazepine
ModerateCarbamazepine can lower the amount of ponatinib in your blood. It does this by speeding up the liver enzyme (CYP3A4) that breaks ponatinib down. Because of this, ponatinib may not work as well as it should when the two are taken together. Tell your doctor or pharmacist if you are taking carbamazepine with ponatinib.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.