Dabiran Dabigatran Etexilate Mesylate Dronedarone
ModerateIf you take Dabigatran Etexilate Mesylate after hip replacement surgery to prevent blood clots in the legs and lungs, and you also take Dronedarone, the two may need to be spaced apart. Dronedarone is a P-gp inhibitor. This means it can stop the body from clearing dabigatran normally. If your kidney function is fine (CrCl 50 mL/min or higher), it may help to take Dabigatran Etexilate Mesylate and Dronedarone a few hours apart. The same advice applies to other P-gp inhibitors, such as ketoconazole taken by mouth. Ask your doctor or pharmacist for the exact timing.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.