Ponatigen Ponatinib Hydrochloride Clarithromycin
ModerateClarithromycin is a strong CYP3A inhibitor, which means it slows down an enzyme the body uses to process ponatinib. So be careful if you take the two together. Your doctor may think about lowering the starting dose of ponatinib to 30 mg. Don't change the dose yourself. Let your doctor decide.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.