Degaris Degarelix Acetate Dofetilide
MajorDegarelix lowers male hormone levels, and this kind of treatment may lengthen the QTc interval, which is a measure of the heart's electrical rhythm on an ECG. Dofetilide is a class III antiarrhythmic medicine that also affects this rhythm and can trigger torsades de pointes, a dangerous irregular heartbeat. So if you take degarelix together with dofetilide, the doctor should think about it carefully before combining them. The same caution applies to other medicines that lengthen the QTc interval, such as class IA antiarrhythmics (quinidine, disopyramide), other class III antiarrhythmics (amiodarone, sotalol, ibutilide), methadone, moxifloxacin and antipsychotics.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.