Docetaxel AqVida Docetaxel Trihydrate Ketoconazole
MajorStrong CYP3A4 inhibition reduces docetaxel clearance, increasing neutropenia and toxicity.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Avoid; if unavoidable, reduce docetaxel dose by about 50% with close monitoring.