Bisoren contains Bisoprolol Hemifumarate Diltiazem Hydrochloride
MajorRisk of severe bradycardia, AV block and heart failure.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid or monitor heart rate, ECG and BP closely.