Dinosen Dienogest Saquinavir
ModerateSaquinavir is a protease inhibitor. It is also one of the known CYP3A4 inhibitors, which are medicines that slow down the CYP3A4 liver enzyme that breaks down many drugs. Dienogest is a progestogen, so taking it with saquinavir may raise its level in your blood. A higher level can cause more side effects. Other medicines in this group include ritonavir, indinavir and nelfinavir, which are also protease inhibitors, along with azole antifungals, macrolides, cimetidine, verapamil, diltiazem and some antidepressants.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.