Calcent Acalabrutinib Omeprazole
ModerateWhen acalabrutinib is taken together with omeprazole (40 mg a day for 5 days), the level of acalabrutinib in the body drops. The leaflet says this happens because omeprazole lowers the AUC of acalabrutinib by 43%, where AUC is a measure of how much of the medicine the body is exposed to over time.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.