Zytiga Abiraterone Acetate Pioglitazone
ModerateIn a study of healthy volunteers, a single 1,000 mg dose of abiraterone acetate raised the amount of pioglitazone in the body by 46%. Both medicines are handled by the same liver enzyme, so pioglitazone builds up more than usual.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor or pharmacist before taking these together. They may check you or change the plan. Do not change or stop either medicine yourself.