Utramal Tramadol Hydrochloride Alprazolam
MajorProfound sedation, respiratory depression, coma and death.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid if possible; use the lowest doses and shortest duration with monitoring.