Eval CR Sodium Valproate Phenobarbital
ModerateValproate raises phenobarbital levels, causing excess sedation; phenobarbital may lower valproate.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
Clinical management: Monitor sedation and drug levels; reduce phenobarbital dose if needed.