Xpos Posaconazole Rifamycin
ModerateTaking Posaconazole with Rifamycin antibacterials (Rifampicin, Rifabutin) can significantly lower the level of Posaconazole.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor or pharmacist before taking these together. They may check how well your posaconazole works or change the plan.