Anleptic Carbamazepine Crizotinib
MajorCarbamazepine is one of the medicines that can lower the level of crizotinib in the blood. Carbamazepine belongs to a group of drugs that speed up the breakdown of crizotinib by the liver enzyme CYP3A, so crizotinib may not work as well. Doctors generally advise avoiding taking the two together, and this is not a complete list of such medicines.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.