Ambrisan Ambrisentan Cyclosporine
ModerateTaking Ambrisentan and Cyclosporine together over several doses roughly doubles the amount of Ambrisentan in the body (about 2-fold, in healthy volunteers). Because of this, when the two are taken together, the Ambrisentan dose should be limited to 5 mg once daily.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.