Paltab Palbociclib Cyclosporine
ModeratePalbokin (Palbociclib) can raise the amount of Cyclosporine in your body. Cyclosporine is a CYP3A substrate with a narrow therapeutic index. That means the gap between a helpful dose and a harmful one is small, so even a modest rise in its level matters. Your doctor may need to lower your Cyclosporine dose if you take it with Palbokin.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.