Orzolol Dorzolamide + Timolol Amiodarone Hydrochloride
ModerateWhen Dorzolamide + Timolol is used together with amiodarone, the two can add to each other's effect and cause blood pressure to drop and the heart rate to slow down. The same thing can happen with other medicines in these groups: calcium channel blockers taken by mouth, catecholamine-depleting drugs or β-blockers, digitalis glycosides, parasympathomimetics, narcotics, and MAOIs.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.