ALK Brigatinib Saquinavir
MajorSaquinavir is a strong CYP3A inhibitor, which means it slows down the enzyme that your body uses to break down Brigatinib. If the two are taken together, more Brigatinib can stay in your blood than intended, which may raise the chance of side effects. The leaflet says this combination should be avoided. Do not start or stop either medicine on your own; talk to your doctor or pharmacist first.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.