Taking axitinib together with dexamethasone can lower the amount of axitinib in your body. Dexamethasone speeds up the enzymes (CYP3A4/5) that break axitinib down, so the medicine may not work as well as it should.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.