Informational only — Not medical advice. Always consult a licensed healthcare provider.

Shasthya স্বাস্থ্য · Health, made simple
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Community data Updated 23 hours ago
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Indications

Eplon is used for the short-term treatment of insomnia. In controlled clinical trials, Eplon was shown to shorten the time it takes to fall asleep, and this effect was seen for up to 30 days.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Zaleplon is a newer hypnotic that is not a benzodiazepine. It belongs to the pyrazolopyrimidine class, so its chemical structure has no relation to benzodiazepines, barbiturates or other drugs known to have hypnotic properties. Zaleplon acts on the gamma aminobutyric acid-benzodiazepine (GABA-BZ) receptor complex.

Pregnancy & Breastfeeding

Pregnancy: Zaleplon has not been studied in pregnant women, so it is not recommended during pregnancy. It has no established use in labour and delivery either.

Lactation: A study in breastfeeding mothers found that the clearance and half-life of Zaleplon were similar to those in young healthy subjects. A small amount of Zaleplon passes into breast milk, and the highest amount appears in the feed about 1 hour after the dose is taken. Even this small amount may reach concentrations in the infant that could matter, and the effects of Zaleplon on a nursing infant are not known. For these reasons, Zaleplon is not recommended for nursing mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Zaleplon dose should be set for each person. For most adults who are not elderly, the recommended dose is 10 mg. Some low weight people may do well enough on 5 mg. The risk of certain side effects seems to rise with the dose, but 20 mg has been shown to be tolerated adequately, and it may be considered for the occasional patient who gets no benefit from a trial of a lower dose. Doses above 20 mg have not been properly evaluated and are not recommended. Take Zaleplon immediately before bedtime. If it is taken with or straight after a heavy, high fat meal, it is absorbed more slowly, and its effect on sleep latency would be expected to be smaller. Elderly and debilitated patients seem to be more sensitive to hypnotics and respond to 5 mg of Zaleplon. So 5 mg is the recommended dose for them, and doses over 10 mg are not recommended. For patients with mild to moderate renal impairment, no dose adjustment is necessary. Patients who are also taking Cimetidine should be given an initial dose of 5 mg, because Zaleplon clearance is reduced in this group. Pediatric use: the safety and effectiveness of Zaleplon in pediatric patients have not been established.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.