Vitamin B1, B6 & B12

Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy. It also promotes healthy nerves, improves mood and strengthens the heart. Vitamin B6 forms RBCs, helps cells to make proteins, manufactures neurotransmitters (e.g. serotonin) and releases stored forms of energy. It helps to prevent CVS diseases and stroke, helps to lift depression and eases insomnia. Vitamin B12 is essential for cell replication and important for RBC production. It prevents anemia, helps to prevent depression, reduces nerve pain, numbness and tingling, and lowers the risk of heart diseases.

The vitamins in Vitamin B1, B6 and B12 are absorbed well when taken by mouth. They are widely distributed to most tissues and appear in breast milk. Inside the cell, thiamine is mostly present as diphosphate. The body does not store thiamine to any appreciable extent, so amounts beyond what the body needs are excreted in the urine, either as unchanged thiamine or as metabolites.

Pyridoxine, pyridoxal and pyridoxamine are readily absorbed from the GIT after oral administration and are converted to the active forms, pyridoxal phosphate and pyridoxamine phosphate. They are stored mainly in the liver, where they are oxidised to 4-pyridoxic acid and other inactive metabolites, and these are excreted in the urine. As the dose goes up, proportionally greater amounts are excreted unchanged in the urine.