Undenatured Type II Collagen

Undenatured Type II Collagen comes from chicken sternum cartilage. It is made by a patented, low-temperature, non-enzymatic process that keeps the natural triple helix molecular configuration and the biological activity of the collagen. Its mechanism of action is unique. The molecules of undenatured collagen II carry active binding sites called epitopes, and these start a process called oral tolerization.

In oral tolerization, the active epitopes interact with the Peyer's patches (lymphoid tissue) of the small intestine, which then release collagen-specific regulatory T-cells. These cells travel to the joint areas and prevent the release of T-cells. Preventing the release of T-cells stops macrophages from secreting collagenase enzymes, the enzymes responsible for breaking down collagen in joint cartilage. The production of inflammatory cytokines also slows down. This reduces inflammation, halts the erosion of joint cartilage and promotes cartilage rebuilding.

Undenatured Type II Collagen supports joint function, mobility and flexibility. It also improves knee extension by up to 10%, which gives a better range of motion, and it relieves joint pain caused by strenuous exercise.