Tirofiban Hydrochloride

Adults: Give 25 mcg/kg intravenously within 5 minutes, then continue with 0.15 mcg/kg/min. For patients with serum creatinine ≤60 mL/min, the continuing rate is 0.075 mcg/kg/min. The infusion can run for up to 18 hours. Pediatric use: safety and effectiveness in pediatric patients have not been established. Important administration instructions: Tear off the foil overpouch to open the container. The plastic may look somewhat opaque because it absorbs moisture during sterilization, and this opacity fades gradually. Squeeze the inner bag firmly to check for leaks. If you find any leak, or if sterility is in doubt, discard the solution. The solution must be clear and the seal intact before use. Hang the container from its eyelet support, take the plastic protector off the outlet port, and attach a conventional administration set. AGGRASTAT can be given in the same intravenous line as atropine sulfate, dobutamine, dopamine, epinephrine hydrochloride (HCl), famotidine injection, furosemide, lidocaine, midazolam HCl, morphine sulfate, nitroglycerin, potassium chloride, and propranolol HCl. It must not go through the same IV line as diazepam. Don't add other drugs to the bag, and don't remove solution from it directly with a syringe. Plastic containers should not be used in series connections, because air can be drawn from the first container once it is empty of solution, and this can result in air embolism. Throw away any unused portion left in the bag.