Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Tiagra is used to treat erectile dysfunction (ED), the symptoms of an enlarged prostate (benign prostatic hyperplasia, or BPH), and cases where both conditions occur together.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Tadalafil works by selectively blocking an enzyme called phosphodiesterase type 5 (PDE5). Blocking this enzyme raises levels of a signalling molecule called cGMP in smooth muscle cells. Higher cGMP relaxes smooth muscle and increases blood flow into the penis, which produces an erection.

PDE5 is also found in the smooth muscle of the prostate and bladder wall. By blocking PDE5 in these tissues as well, tadalafil raises cGMP levels there too, relaxing the smooth muscle of the prostate and bladder. This relaxation can improve blood flow to the urinary tract and help the bladder neck open more widely, making it easier to pass urine.

Pregnancy & Breastfeeding

Tadalafil falls under pregnancy category B as assigned by the USFDA. It is only recommended for use during pregnancy when the benefit outweighs the risk. There is no data on whether Tadalafil passes into human breast milk, so caution is advised when giving it to nursing mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For most people with erectile dysfunction, the usual starting dose of tadalafil is 10 mg. Depending on how well it works, the dose can be raised to 20 mg or lowered to 5 mg. Tadalafil should not be taken more than once a day. It keeps working for up to 36 hours. For benign prostatic hyperplasia, the recommended dose is 5 mg, taken at the same time every day. When erectile dysfunction and benign prostatic hyperplasia are treated together, the combined dose is also 5 mg, taken at the same time every day.

Side Effects & Interactions