Indications
Scabies Infestations Spinosa Topical Suspension is a scabicide. It is indicated for the topical treatment of scabies infestations in adult and paediatric patients 4 years of age and older. Head Lice Infestations Spinosa Topical Suspension is also a pediculicide, and it is indicated for the topical treatment of head lice infestations in adult and paediatric patients 6 months of age and older.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Spinosad causes neuronal excitation in insects. After a period of hyperexcitation, lice and mites become paralysed and die. When it is applied to the skin, very little spinosad gets into the bloodstream, and plasma levels are either very low or absent. In clinical studies, plasma concentrations were below the level of quantification in most subjects after a single application to the scalp for lice treatment. Children show a similar pattern, with minimal systemic exposure. The medicine stays in the treated area, where it targets lice and scabies on the surface of the skin and scalp. Because so little is absorbed, it is not distributed in any significant way into the systemic circulation, and metabolism in the body is very limited. If trace amounts are absorbed, they are likely metabolised by the liver's CYP450 enzyme system. Most of the drug leaves unchanged, through the skin or by external means (for example, when it is washed off). Minimal amounts, if any, are excreted in urine or feces, again because absorption is low. For the same reason, the systemic half-life is not well defined in humans. The drug mainly stays active on the surface of the skin until it is washed off.
Pregnancy & Breastfeeding
Spinosad is in pregnancy category B. Breastfeeding isn't expected to expose the child to Spinosad. Even so, a breastfeeding mother should wash Spinosad Topical Suspension off the breast with soap and water before she feeds the baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.