Indications
Sotagliflozin is used alongside insulin to improve blood sugar control in adults with type 1 diabetes mellitus. It is meant for people with a Body Mass Index (BMI) of 27 kg/m2 or above, whose blood sugar has not come under adequate control even though their insulin therapy has been optimal.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Sotagliflozin is a tablet taken by mouth that blocks two transporters, SGLT1 and SGLT2. It improves blood glucose and metabolic control by working in two places. In the gut, it blocks SGLT1 locally. In the proximal renal tubule, it blocks SGLT2 throughout the body.
When SGLT1 is blocked in the proximal intestine, glucose is absorbed later and in smaller amounts. This blunts and delays the rise in blood glucose after meals (postprandial hyperglycaemia). When SGLT2 is blocked, the kidney reabsorbs less glucose and the renal threshold for glucose drops, so more glucose leaves the body in the urine.
Pregnancy & Breastfeeding
We have no data on Sotagliflozin use in pregnant women. We also have no human data on whether Sotagliflozin passes into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.