Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Sodium Picosulfate

Stimulant Laxative Prescription
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Indications

Constipation

Sodium Picosulfate is used for constipation of any etiology. It is also used for relief from prolonged and recurrent constipation. Doctors also use it for bowel clearance before surgery, childbirth or radiological investigations.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sodium Picosulfate is a stimulant laxative from the triarylmethane group. You take it by mouth, and the bacteria in the colon activate it, so it acts locally in the colon. The active form stimulates the nerve endings in the intestinal wall. This brings on colonic peristalsis and helps water and electrolytes collect in the colonic lumen. The result is that defecation is stimulated, transit time is reduced and the stool becomes softer.

Sodium Picosulfate also acts on the rectum, where stimulation increases motility and gives a feeling of rectal fullness. This rectal effect may help to restore the "call to stool".

Pregnancy & Breastfeeding

There are no reports of harmful effects on the pregnancy or the foetus that can be put down to sodium picosulfate. Even so, the medicine should be avoided during the first trimester. Clinical data show that neither the active part of sodium picosulfate (BHPM, or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides passes into the milk of healthy breastfeeding women.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Sodium Picosulfate is taken by mouth, and the doses below are meant to be taken at night so that you pass stool the next morning. Start with the lowest dose. You can then adjust it up to the maximum recommended dose until your stools are regular. Don't go above the maximum recommended daily dose. 10 mg tablet dose: Adults and children over 10 years of age take 5-10 mg per day. Children aged 4-10 years take 2.5-5 mg per day. Oral Solution (5 mg/5 ml) dose: Adults and children over 10 years of age take 5-10 ml or one to two teaspoonful per day. Children aged 4-10 years take 2.5-5 ml or half to one teaspoonful per day. Children from one month to 4 years of age take 0.25 ml/kg body weight per day. Concentrated Oral Solution (7.5 mg/ml) dose: Adults and children over 10 years of age take 0.67-1.33 ml per day. Children aged 4-10 years take 0.33-0.67 ml per day.