Informational only — Not medical advice. Always consult a licensed healthcare provider.

Shasthya স্বাস্থ্য · Health, made simple
বাং
Community data Updated 23 hours ago

Sodium Feredetate Trihydrate

Oral Iron preparations Prescription
Check interactions
🌐 বাংলায় দেখুন

Indications

Rheumatoid Arthritis Anemia

Sodium Feredetate Trihydrate syrup (sold as S-Fer syrup) is an oral solution for adults, children and babies. It treats iron deficiency anemia, which is caused by too little iron in the body. The form of iron in Sodium Feredetate Trihydrate is less likely to upset the stomach than other iron-containing medicines, and it will not discolour teeth. It is indicated for iron deficiency anemia, especially in children. It is also used in pregnant women when other forms of oral iron may not be well tolerated, and in people who have become anemic as a result of rheumatoid arthritis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sodium Feredetate isn't an iron salt, because the iron in it is in an un-ionised form. The iron is "insulated" or "sequestered" with the sodium salt of Ethylenediamine Tetra-Acetic Acid (EDTA), which forms a chelate, and this is why it does not discolor teeth. Inside the gastro-intestinal tract the chelate splits and releases elemental iron.

After absorption, 60% to 70% of the elemental iron goes into haemoglobin. Most of the remainder is held in storage forms, either as ferritin or haemosiderin, in the reticulo-endothelial system and, to a lesser extent, in hepatocytes. A further 4% is present in myoglobin and haeme-containing enzymes, or bound to transferrin in plasma. EDTA is poorly absorbed, and after it reaches the bloodstream it passes through the body unchanged.

Pregnancy & Breastfeeding

Giving any medicine in the 1st trimester of pregnancy calls for a careful look at the possible risks against the benefits. For Sodium Feredetate Trihydrate, no adverse events have been reported during pregnancy or while breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Sodium Feredetate Trihydrate is given by mouth as an oral solution for iron-deficiency anaemia. For treatment, a neonate can have up to 2.5 mL twice daily, and smaller doses should be used at the start. The same applies to a child aged 1 to 11 months: up to 2.5 mL twice daily, starting with smaller doses. At 1 to 4 years the dose is 2.5 mL 3 times a day, and at 5 to 11 years it is 5 mL 3 times a day. For ages 12 to 17 years, the dose is 5 mL 3 times a day, increased to 10 mL 3 times a day, and the increase should be made gradually. For prevention (prophylactic use), a neonate is given 1 mL daily. Iron supplementation may be required in babies of low birth-weight who are solely breast-fed. It is started 4 to 6 weeks after birth and continued until mixed feeding is established. The dose is the same, 1 mL daily, for a baby aged 1 to 11 months, with the same note: prophylactic iron supplementation may be required in low birth-weight babies who are solely breast-fed, started 4 to 6 weeks after birth and continued until mixed feeding is established.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.