Indications
Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate is used for gastric reflux, heartburn and indigestion. It is also used for flatulence that comes with gastric reflux, and for heartburn of pregnancy. Doctors also use it in all cases of epigastric and retrosternal distress where the underlying cause is gastric reflux.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate is a combination of two antacids (Calcium Carbonate and Sodium Bicarbonate) and an alginate (Sodium Alginate). The suspension works in two ways, neutralizing excess stomach acid to relieve the pain and discomfort, and forming a protective barrier over the stomach contents to soothe the burning pain in your chest. Its mode of action is physical and doesn't depend on absorption into the systemic circulation.
The product combines two antacids (Calcium Carbonate and Sodium Bicarbonate) with an Alginate. Once swallowed, it reacts rapidly with gastric acid and forms a raft of Alginic Acid gel with a near neutral pH. Studies have shown that the raft interacts with and caps the acid pocket in the stomach, which reduces esophageal acid exposure. The raft floats on the stomach contents and impedes gastro-esophageal reflux for up to 4 hours, protecting the esophagus from Acid, Pepsin and Bile. In severe cases the raft itself may be refluxed into the esophagus in preference to the stomach contents, and it then exerts a demulcent effect.
In vitro evidence has also shown that the raft has a secondary action. It can entrap bile and pepsin within its structure, which protects the esophagus further from these gastric components.
Calcium Carbonate neutralizes gastric acid and gives fast relief from indigestion and heartburn. Sodium Bicarbonate also has a neutralizing action, so adding it increases this effect.
Pregnancy & Breastfeeding
Pregnancy: Studies in more than 500 pregnant women, along with a large amount of post-marketing data, show no malformations and no toxicity to the foetus or newborn from the active ingredients of this medicine. It can be used during pregnancy if it is clinically needed.
Breastfeeding: No effects of the active substances have been seen in breastfed newborns or infants of treated mothers. The medicine can be used during breastfeeding.
Fertility: Pre-clinical studies show that alginate has no negative effect on the fertility or reproduction of parents or their offspring. Clinical data do not suggest that this medicine affects human fertility.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.