Indications
Tralin tablet is used to treat major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder (PD), post-traumatic stress disorder (PTSD), social anxiety disorder (SAD) and premenstrual dysphoric disorder (PMDD).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Sertraline strongly and selectively blocks the reuptake of 5-HT by neurons in the CNS. This raises the 5-HT concentration at the synaptic clefts, so its activity at the postsynaptic receptor sites is sustained for longer. In the end, depression improves. Sertraline also reduces serotonin turnover in the brain, and this is another factor thought to contribute to how it works. Because its elimination half-life is long, it can be given once daily.
Pregnancy & Breastfeeding
Animal studies showed no evidence that Sertraline causes teratogenicity, but that doesn't settle the question, because its safety during human pregnancy has not been established. Sertraline is known to pass into breast milk, and what it does to a nursing infant has not yet been established. So if treatment with Sertraline is considered necessary, stopping breast-feeding should be considered.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.